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Cognitive Abilities
Internal consistency
Test-retest reliability
Shifting
0,726
0,842
Divided Attention
0,866
0,85
Width of Field of View
0,806
0,998
Hand-eye Coordination
0,779
0,876
Naming
0,687
0,782
Focused Attention
1
0,905
Visual Scanning
0,862
0,922
Estimation
0,761
0,986
Inhibition
0,661
0,697
Phonological Short-term Memory
0,915
0,698
Contextual Memory
0,884
0,775
Visual Short-Term Memory
0,866
0,743
Short-Term Memory
0,853
0,721
Working Memory
0,85
0,696
Non-verbal Memory
0,787
0,73
Spatial Perception
0,611
0,907
Visual Perception
0,751
0,882
Auditory perception
0,652
0,904
Planning
0,765
0,826
Recognition
0,864
0,771
Response Time
0,873
0,821
Processing Speed
0,888
0,764
Cognitive Assessment for Chemo Fog Research (CAB-CF)

Reliability analysis of the evaluation (Only in English)Download

Cognitive Assessment for Chemo Fog Research (CAB-CF)

Innovative neuropsychological assessment for Chemo Brain allows for a complete cognitive screening and evaluation to detect the risk index of suffering from cognitive deterioration after an oncological process.

Who is it for?

This product is not for sale. This product is for research purposes only. For more info see CogniFit Research Platform

Multi-platform

Cognitive Assessment for Chemo Fog Research (CAB-CF)

You are going to create a patient management account. This account is designed to give your patients access to CogniFit evaluations and training.

You are going to create a student management account. This account is designed to give your students access to CogniFit evaluations and training.

You are going to create a research account. This account is specially designed to help researchers with their studies in the cognitive areas.

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Number of assessments*

* Assessment licenses can be used for any type of assessment

 

What is the CogniFit Chemo Brain Test?

What is the CogniFit Chemo Brain Test?

  • Evaluate the risk index of the presence of Chemo Brain
  • For adults of all ages
  • Takes about 30-40 minutes to complete
  • Reliability analysis of the evaluation - Only in English Download

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) from CogniFit is a leading professional test that uses clinical and validated tasks designed to quickly and accurately detect the presence of symptoms, traits, or dysfunctions in the cognitive processes affected by cancer treatment.

This innovative Chemo Brain test is a scientific resource that makes it possible to take a complete cognitive screening, understand cognitive strengths and weaknesses, and evaluate the risk index for the presence of Chemo Brain (or Chemo Fog). This test is suitable for people 18 years and older, like young adults, adults, or seniors who have undergone cancer treatment and may present related cognitive decline. Anyone can easily use this neuropsychological assessment battery. The results of this assessment will automatically be available after completing the test, which usually lasts about 30-40 minutes.

Cancer is one of the most devastating diseases that we have today, and the treatments for it can be aggressive for the patient. These treatment processes can noticeably weaken different cognitive skills, affecting daily life. The detection of this cognitive deterioration is an important part of the intervention and correction of this cognitive decline, and the earlier that you work to improve the skills, the better chance there is of recovering cognitive function and independence.

A clinical consultation and history, questionnaires, clinical evaluation scales, and clinical test are all effective tools for detecting certain cognitive problems, but they are able to detect the degree to which these cognitive skills are affected. A clinically validated neuropsychological assessment can help perform an exhaustive assessment of the different cognitive functions affected by cancer treatments. Note that CogniFit does not directly offer a medical diagnosis of chemo fog but the neuropsychological assessment can help perform a screening of different cognitive functions. We recommend using this Chemo Brain test to complement a professional assessment, and never to replace a clinical consultation.

Phases of this Chemo Brain Test (CAB-CF)

Phases of this Chemo Brain Test (CAB-CF)

This complete cognitive evaluation to detect Chemo Fog and Chemo Brain are made up of a questionnaire and a complete battery of neuropsychological tests. It usually takes about 30-40 minutes to complete.

Any adult who has undergone chemotherapy treatment will answer the questionnaire in order to evaluate the clinical signs and symptoms related to these cognitive alterations. After the questionnaire, a series of validated tasks presented as online games will appear on the screen for the user to complete.

Well-being Questionnaire

A series of simple questions designed to detect the main symptoms of Mental Fog will be presented. This questionnaire is an evaluation tool adapted to the effects of Chemo Brain.

Neuropsychological factors and cognitive profile

The CAB-CF continues with a battery of tasks aimed at evaluating the main neuropsychological factors identified in the scientific literature surrounding this disorder. The results will be compared to other users of the same age and gender.

Complete results report

After completing the Chemo Brain test, a detailed report will be available to download, where the user's risk index for Mental Fog will appear, along with a description of the warning signs, cognitive profile, and results analysis, and recommendations. These results offer valuable information to help create an appropriate support strategy.

Psychometric Results

Psychometric Results

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) from CogniFit uses patented algorithms and artificial intelligence (AI) that makes it possible to analyze thousands of variables and highlight any risk of Mental Fog with very satisfactory psychometric results.

The cognitive profile in the neuropsychological report has received high reliability, consistency, and stability ratings. The test has been validated through repeated tests and measurement processes. Transversal research designed, like the Cronbach Alpha have been followed, reaching scores of about .9, and the Test-Retest tests received scores of almost 1, which shows the high level of reliability and precision.

See validation table

Who is it for?

Who is it for?

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) can be used by adults of all ages who are receiving or have received chemotherapy.

Any individual or professional can easily use this neuropsychological assessment tool to detect the cognitive alterations caused by a cancer treatment. No specialized training or knowledge of neuroscience or technology systems is necessary to use this test. It is especially designed for:

Individual Users

Know the state of my brain, as well as my strengths or weaknesses

Using CogniFit Chemo Brain Cognitive Assessment Battery, we will be able to know the risk of suffering this consequence of chemotherapy as a cancer treatment. It will be very helpful to know if the cognitive problems we notice are normal for our age, or if they are a symptom of this problem.

Healthcare Professionals

Easily and reliably evaluate patients and offer a complete, detailed report

The neuropsychological Chemo Brain test from CogniFit makes it possible for healthcare professionals to detect, diagnose, and create an intervention for this disorder. Detecting the symptoms of Mental Fog is the first step to identifying the cognitive alterations caused by it, and creating an appropriate cognitive intervention. This powerful software allows you to study multiple variables and offer complete, personalized reports.

Families, caretakers, and individual users

Identify if a loved-one presents a risk of cognitive decline related to Mental Fog

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) is a scientific resource made up of a simple-answer questionnaire and online tasks. This makes it possible for any user, even without specialized training, to evaluate the different symptoms and neuropsychological factors that may be indicative of Chemo Fog. The comprehensive report will help identify the risk of having a cognitive disorder related to chemotherapy and outline specific guidelines for each individual case.

Researchers

Measures the cognitive abilities of study participants

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) makes it possible to precisely measure a wide variety of cognitive skills. CogniFit's technology takes thousands of variables into account from the assessment activities in order to gather reliable information about the participant's cognitive state.

Benefits

Benefits

This online, scientifically based evaluation tool to quickly and reliably assess the symptoms, strengths, weaknesses, and cognitive processes affected by Chemo Brain has a number of advantages:

LEADING INSTRUMENT

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) from CogniFit is a professional resource created by specialists in cognitive alterations. The cognitive tests have been patented and clinically validated. This leading professional tool is used by the scientific community, families, universities, associations and foundations, and medical centers around the world.

EASY-TO-USE

Any professional or individual user can use this assessment battery for Chemo Brain. No special training or background in technology services necessary to assign and use this assessment battery, making it simple and efficient to use from home or at the office.

USER-FRIENDLY

All of the clinical tasks are presented automatically, and are shown as simple, fun, and interactive brain games and exercises, which makes them easy to understand and fun to play, improving comprehension.

DETAILED RESULTS REPORT

The Cognitive Assessment for Chemo Fog Patients (CAB-CF) makes it possible to provide quick and reliable information. This report is easy to understand and makes it possible to see and understand the clinical symptoms, strengths and weaknesses, and risk index for having Chemo Fog.

ANALYSIS AND RECOMMENDATIONS

This powerful software allows you to analyze thousands of variables and offer specific recommendations for each user's needs and type of deterioration.

When should you use this Chemo Brain test?

When should you use this Chemo Brain test?

This assessment battery makes it possible to reliably detect the symptoms and level of cognitive deterioration related to Chemo Fog in adults and seniors.

Without the proper intervention and help, Chemo Fog may start to affect a person's professional, personal, and family areas.

Chemo Fog may cause generalized deterioration and difficulties at work or at home. We can differentiate between:

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Most representative symptoms
Description
V2_ASSESS_Test-quimioneblina_CASES_SINT_1
Symptoms of Chemo Brain
Emotional Symptoms
Physical Symptoms

Symptoms of Chemo Brain

This term is used to describe the changes in memory, attention, and concentration, and the ability to do different mental tasks that are related to chemo or hormone therapy treatment for cancer. Other factors aside from medication can also play a role in these cognitive deficits, like age, gender, and the type of cancer.

Emotional Symptoms

A cancer diagnosis and its progression can cause considerable psychological distress and patients and their families. Studies show that between 25% and 50% of patients diagnosed with cancer will experience varying levels of emotional distress. Recent studies have shown that there is a higher presence of depression, anxiety, and emotional distress in cancer patients than the general population.

Physical Symptoms

Both the treatment and the disease itself can cause physical, digestive, metabolic, motor and sleep changes, as well as an alteration in how one sees their self-image. These changes may have a lesser or greater effect on the patient.

V2_ASSESS_Test-quimioneblina_CASES_SINT_1_4

V2_ASSESS_Test-quimioneblina_CASES_SINT_1_4_A

V2_ASSESS_Test-quimioneblina_CASES_SINT_1_5

V2_ASSESS_Test-quimioneblina_CASES_SINT_1_5_A

V2_ASSESS_Test-quimioneblina_CASES_SINT_1_6

V2_ASSESS_Test-quimioneblina_CASES_SINT_1_6_A

Description of the diagnostic criteria questionnaire

Description of the diagnostic criteria questionnaire

Mental Fog or Chemo Brain is characterized by a series of clinical symptoms. These indicators can help better understand the presence of this disorder, which is why the first part of the Cognitive Assessment for Chemo Fog Patients (CAB-CF) is a questionnaire that adapts to the main diagnostic symptoms of Chemo Fog for each age range.

The questions in this questionnaire are similar to what one may find in a diagnostic manual, clinical questionnaire, or scales for Chemo Fog. However, the questions have been simplified to be easily understood by any user.

Diagnostic Criteria for Chemo Brain for Adults and Seniors

Made up of a series of simple questions that can be completed by the professional responsible for the assessment or the person taking the Chemo Brain test. The questionnaire covers the following domains: Emotional symptoms (psychological distress, like anxiety or depression), Physical symptoms (changes in self-image, metabolic changes, sleep changes, fatigue, muscle pain, etc.), and Chemo Fog symptoms (problems with different cognitive skills, like memory or attention).

What cognitive skills are assessed with this Chemo Brain test?

What cognitive skills are assessed with this Chemo Brain test?

The presence of alterations in some cognitive skills may be an indicator of Chemo Brain. A general profile of the cognitive skills may help you understand the severity of the cognitive alterations caused by this disorder. The cognitive domains most altered by cancer treatment, and thus assessed in the Cognitive Assessment for Chemo Fog Patients (CAB-CF) are:

Evaluated Cognitive Domains
Cognitive Abilities

Attention

Ability to filter distractions and focus on relevant information.

Excellent

8.3% above average

Focused Attention

Focused attention and Chemo Brain. Focused attention is the ability to focus attention on one target stimulus, independently of the duration. Poor attention and problems concentrating are frequent complaints of people who have undergone cancer treatment. This attention deficit influences daily life, like when reading a book, following a conversation, or watching TV.

729Your Score

400Average

Memory

Ability to retain or manipulate new information and recover memories from the past.

Excellent

8.5% above average

Short-Term Memory

Short-term memory and Chemo Brain. Short-term memory is the ability to hold onto a small amount of information over a short period of time, like when we remember the beginning of a sentence in order to make sense of the sentence as a whole. A problem in short-term memory may alter one's ability to understand what they hear or impede their ability to correctly understand the information that they receive. According to research, cancer patients have noticed an alteration in their short-term memory after treatment.

745Your Score

400Average

Coordination

Ability to efficiently carry-out precise and organized movements.

Excellent

8.3% above average

Response Time

Reaction time and Chemo Brain. Reaction time is the ability to perceive, process, and respond to a simple stimulus, like answering a specific question. People who have undergone hormone or chemotherapy often talk of a "mental fog", as if they weren't able to think clearly, which manifests itself as a slow response time, as it's likely that they have more trouble forming fluid and correct responses.

659Your Score

400Average

Perception

Ability to interpret the stimuli from one's surroundings.

Excellent

7.7% above average

Spatial Perception

Spatial perception is the ability of human beings to be aware of their relationship with the environment and the space that surrounds us. Although it is true that cognitive alterations can vary depending on the type of cancer and genetic variables, problems have been consistently found in the spatial capacity of users, both during treatment and after treatment.

602Your Score

400Average

Reasoning

Ability to efficiently use (organize, relate, etc.) acquired information.

Excellent

7.9% above average

Planning

Planning and Chemo Brain. Planning is the ability to mentally organize the best way to reach a certain future goal, like when you think about how to tell a story to your friends. The Chemo Fog effect described alterations in planning, which may cause problems structuring thoughts, ideas, daily activities, or any other task that requires a certain amount of planning and organization.

697Your Score

400Average

Processing Speed

Processing speed can be defined as the time it takes a person to do a mental task. That is, the processing speed is the time it takes between when the stimulus is received and a response is emitted. Processing speed is one of the most commonly reported capabilities in chemotherapy-related cognitive dysfunction, since people who have undergone type of treatment tests usually require a greater amount of time to process the information than healthy people.

673Your Score

400Average

Evaluation tasks

Our Digital Cognitive Assessments

CogniFit digital tests are designed to measure a specific areas of cognition and are grouped together to form customized batteries based on the unique requirements of the study design and population. Learn more about our different tests and how they can support the unique needs of your study by exploring the details and demos below.

Tapping Test

The Speed Test REST-HECOOR exercise was inspired by the classic test of Fingertip tapping from the assessment battery NEPSY (Korkman et al., 1998). The test-taker is required to keep on clicking for 10 seconds and as rapidly as possible with the mouse, or finger if using a touch-screen device, in a defined area on the screen. Data is collected as the number of clicks during the allocated time, number of clicks inside the defined area and number of clicks outside it.

Psychomotor Vigilance Test

The Resolution Test REST-SPER was inspired by the classic paradigms Go/No Go Task (Gordon & Caramazza, 1982), Continuous Performance Test (Conners, 1989; Epstein et al., 2001), and the Psychomotor Vigilance Task (Dinges & Powell, 1985). The test-taker is required to rapidly press on circles which appear on the screen and to ignore hexagons should they also appear. Embedded in the task are 16 circles-only items and 8 circles-and-hexagons items. For each item data is collected on response time, response accuracy and cursor distance from target center.

Visual Working Memory Span Test

The Concentration Test VISMEM-PLAN took as a reference the Corsi block-tapping test (Corsi, 1972; Kessels et al., 2000; Wechsler, 1945). In the first part of the task, some circles, within a fixed array of circles, light up. The test-taker is required to memorize which circles, within the array, have lit up and then try to reproduce the sequence in the right order. In the second part of the task, a delay of 4 secs is added between the first screen and the playback screen, in order to increase the time the user must retain the information.

Digit Span Test

The Sequencing Test WOM-ASM is based on the classic direct and indirect digit test of the WAIS-III (Wechsler, 1997). The test-taker is required to remember and reproduce increasingly longer number sequences, which appear, each in its turn, on the screen. The task will begin with a two- -number sequence.

Visual Memory Test

The Recognition Test WOM-REST is based on the classic tests of Symbol search (WAIS) (Wechsler, 1997), Wisconsin Card Sorting Test (WCST) (Heaton, 1981) and Raven's Progressive Matrices Test (Raven, 1936). In this task, a trio-sequence of objects is presented in the center of the screen. The test-taker is required to memorize these stimuli in a first screen, and to recognize it from among four trio-sequences in a second screen. The number of correct answers is considered to calculate an accuracy percentage.

Number-Size Congruency Test

The Processing Test REST-INH was inspired by the classic Stroop test (Stroop, 1935). The test-taker is required to press on the larger of two circles, regardless of the number inscribed in each circle, while ignoring the text that could appear on the top-middle part of the screen. They are then required to press on the higher number regardless of the size of the circle in which the number is inscribed.

Stroop Test

The Equivalencies Test INH-REST was based on the classic Stroop test (Stroop, 1935). The test-taker is asked to press on the spacebar (go action) only if the color names on the screen are printed in the matching color and to refrain from pressing (no-go) if the color of the letters does not match the printed color name.

Naming Test

The Decoding Test VIPER-NAM was inspired by the Boston Naming Test (Kaplan et al., 1983) and by the vocabulary test from the WAIS-III (Wechsler, 1997). The test-taker is required to click on the first letter, among four of them, that spells the name of the object depicted on the screen. For example, for the picture of an apple, the test-taker should click on the letter “A” but not on the three incorrect responses (C, P, M) also present on the screen.

Chemo Fog and The Brain

Chemo Fog and The Brain

The cognitive problems related to Mental Fog or Chemo Brain are based on determined brain alterations. Unlike other disorders, the specific brain areas affected by Chemo Fog have not been identified, but rather, damage to the brain on the whole. This is why a general division makes it possible to distinguish between the alterations in the gray matter (neural nuclei) and white matter (neural axons). Few studies have been conducted with respect to the effect that certain drugs used in cancer treatments may cause, but there are some robust conclusions.

  • Difficulty concentration and thinking clearly
  • Problems multi-tasking (doing multiple things at the same time)
  • Problems remembering words during a conversation
  • Slower processing speed when learning new things
  • Difficulty concentrating
  • Difficulty organizing oneself or feeling mentally "fuzzy"

Because of this symptomology, we can infer that some of the brain structures affected are:

1 Prefrontal Lobe

Is in charge of planning behavior and attending to various stimuli at the same time, remembering recent events, concentration, and structuring thought.

2 White Matter

White matter refers to the set of neural axons. These axons work to connect and help neurons communicate between each other, which means that the information received from one side of the brain can be transmitted to another neuron (or set of neurons) on the other side. Chemotherapy may produce a diffusion in the transmission of information from one neuron to another, which may cause slower processing speed and response time, making it more difficult to carry out daily activities.

Customer Service

Customer Service

If you have any questions about data operation, management or interpretation of our assessments, you can contact us immediately. Our team of professionals will solve your doubts and help you with anything you need.

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References

References

  • Szentmartoni , G., Makkos, Z., & Dank, M. (2018). Chemobrain. Neuropsychopharmacol Hung., 20(3), 112-116.
  • Pearre, D. C., & Bota, D. A. (2018). Chemotherapy-related cognitive dysfunction and effects on quality of life in gynecologic cancer patients. Expert Review of Quality of Life in Cancer Care, 3(1), 19-26.
  • Dutta, V. (2011). Chemotherapy, neurotoxicity, and cognitive changes in breast cancer. Journal of Cancer Research and Therapeutics, 7(3), 264.
  • Ren, X., Boriero, D., Chaiswing, L., Bondada, S., St. Clair, D. K., & Butterfield, D. A. (2019). Plausible biochemical mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”), a condition that significantly impairs the quality of life of many cancer survivors. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1865(6), 1088-1097.
  • Raffa, R. B. (2010b). Is a picture worth a thousand (forgotten) words?: neuroimaging evidence for the cognitive deficits in «chemo-fog’/’chemo-brain». Journal of Clinical Pharmacy and Therapeutics, 35(1), 1-9.
  • Raffa, R. B., & Tallarida, R. J. (2010). Effects on the visual system might contribute to some of the cognitive deficits of cancer chemotherapy-induced ‘chemo-fog’. Journal of Clinical Pharmacy and Therapeutics, 35(3), 249-255.
  • Argyriou, A. A., Assimakopoulos, K., Iconomou, G., Giannakopoulou, F., & Kalofonos, H. P. (2011). Either Called “Chemobrain” or “Chemofog,” the Long-Term Chemotherapy-Induced Cognitive Decline in Cancer Survivors Is Real. Journal of Pain and Symptom Management, 41(1), 126-139.

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